Which psychological disorder features fatigue and feelings of worthlessness among its symptoms?

Major Depressive Disorder is characterized by a range of emotional, cognitive, and physical symptoms, with fatigue and feelings of worthlessness being prominent. Individuals suffering from this disorder often experience a pervasive low mood, lack of energy, and a deep sense of inadequacy or self-disdain. These symptoms can significantly impair their daily functioning and overall quality of life.

The feeling of worthlessness in particular can lead to critical self-evaluation and feelings of hopelessness, which are hallmark features of Major Depressive Disorder. This disorder also often includes other symptoms such as changes in appetite, sleep disturbances, and difficulty concentrating, further contributing to the individual's distress.

In contrast, Generalized Anxiety Disorder primarily manifests through excessive worry and anxiety that interferes with daily activities, without the characteristic depressive symptoms. Schizophrenia is characterized by symptoms like hallucinations or delusions, which are distinctly different from the symptoms of Major Depressive Disorder. Bipolar Disorder involves mood swings between depressive states and manic or hypomanic episodes, but the depressive phase in Bipolar Disorder is more variable and does not inherently include the symptoms of worthlessness as a defining feature.